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Selenium deficiency increases the expression of inducible nitric oxide synthase in RAW 264.7 macrophages: role of nuclear factor-kappaB in up-regulation

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To assess hippocampus-specific alterations with advanced age, the Youdim laboratory performed neuroproteomic profiling of female Wistar rats aged 8 and 27 months by 2DE with MS protein identification (Weinreb et al., 2007)